Yes it's possible, it's done! I installed OBH 5.0.001 in the OMB, without resorting to the backup that had on the disc (OBH 4.4.023), installing everything again, after then I installed it in flash (Uno 4KSE).
Using backup looks bad idea... It was what I did initially and gave problems... perhaps the question of plugins. I only have two incompatible plugins, one of them is fundamental and while not adapted to Duo 4K will continue with 4.4.023.
Maybe someone who can move in this plugin....